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今、世界が注目する医学論文は?

<p><span style="font-family:&apos;Noto Sans&apos;, -apple-system, BlinkMacSystemFont, &apos;Segoe UI&apos;, Roboto, &apos;Helvetica Neue&apos;, Arial, &apos;Noto Sans&apos;, sans-serif, &apos;Apple Color Emoji&apos;, &apos;Segoe UI Emoji&apos;, &apos;Segoe UI Symbol&apos;, &apos;Noto Color Emoji&apos;;">インパクトファクターの高いジャーナルから、世界の研究者が注目する主に疾患に関する論文をご紹介します。</span></p>

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今、世界が注目する医学論文は?
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今、世界が注目する医学論文は?

 


2025.10.31 ADHD

a) Efficacy of guided and unguided web-assisted self-help for parents of children with attention-deficit/hyperactivity disorder and oppositional defiant disorder: A three-arm randomized controlled trial    
b) Psychiatric comorbidity in children and adolescents with ADHD: A systematic review and meta-analysis    
c) Sensory Processing in Individuals With Attention-Deficit/Hyperactivity Disorder Compared to Control Populations: A Systematic Review and Meta-Analysis

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2025.10.31 IBD

a) A Pilot Randomized Control Trial to Assess the Adjunctive Effect of Diet on Response to Advanced Therapies in Patients With Ulcerative colitis    
b) Inflammatory Bowel Diseases-Specific Cognitive Behavioral Therapy Delivered via Telehealth RedUCes Disability: ADEPT (Addressing Disability Effectively with Psychosocial Telemedicine) Pragmatic Randomized Controlled Trial    
c) Results of the 9th Scientific Workshop of the European Crohn's and Colitis Organisation (ECCO): Artificial Intelligence in medical management and precision medicine

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2025.10.31 IBD

a) A biomarker-stratified comparison of top-down versus accelerated step-up treatment strategies for patients with newly diagnosed Crohn’s disease (PROFILE): a multicentre, open-label randomised controlled trial    
b) Scoring indices for assessing endoscopic disease activity in acute severe ulcerative colitis: A systematic review    
c) Endo-Histo foundational fusion model: a novel artificial intelligence for assessing histologic remission and response to therapy in ulcerative colitis clinical trial

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2025.9.30 ADHD

a) Gut microbiome changes with micronutrient supplementation in children with attention–deficit/hyperactivity disorder: the MADDY study    
b) Prefrontal Transcranial Direct Current Stimulation in Pediatric Attention–deficit/hyperactivity disorder: A Randomized Clinical Trial    
c) Attention–deficit/hyperactivity disorder and post-traumatic stress disorder adult comorbidity: a systematic review

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2025.9.30 IBD 

a) Preliminary Results from a Multicenter, Randomized Trial Using Fecal Microbiota Transplantation to Induce Remission in Patients with Mild-to-Moderate Crohn’s Disease     
b) Whole food diet induces remission in children and young adults with mild-moderate Crohn’s disease and is more tolerable than exclusive enteral nutrition: a randomized controlled trial    
c) Impact of diet on Inflammatory Bowel Disease risk: systematic review, meta-analyses and implications for prevention

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2025.9.30 IBD 

a) Diagnostic Accuracy of Non-Invasive Biomarkers and Imaging for Evaluating Postoperative Recurrence in Crohn’s Disease    
b) Gene-Environment Interactions in Inflammatory Bowel Disease: A Systematic Review of Human Epidemiologic Studies    
c) ECCO Topical Review on Predictive Models on Inflammatory Bowel Disease Disease Course and Treatment Response

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2025.8.29 ADHD

a) Research Review: Mechanisms of change and between-family differences in parenting interventions for children with ADHD - an individual participant data meta-analysis    
b) Pilot randomised controlled trial on the feasibility and intervention satisfaction with an educational group programme for adults with Attention-Deficit/Hyperactivity Disorder and their caregivers    
c) Digital health interventions with healthcare information and self-management resources for young people with ADHD: a mixed-methods systematic review and narrative synthesis

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2025.8.29 IBD

a) Virome drift in ulcerative colitis patients: faecal microbiota transplantation results in minimal phage engraftment dominated by microviruses    
b) Development of a capsule endoscopy scoring system for the early diagnosis of small bowel Crohn’s Disease    
c) The Association Between Fast Food Consumption and Inflammatory Bowel Disease: A Case-Control Study and Meta-Analysis

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2025.8.27 IBD

a) ECCO topical review on predictive models on IBD disease course and treatment response    
b) Expert recommendations to standardize transcriptomic analysis in inflammatory bowel disease clinical trials    
c) Colorectal cancer risk in ulcerative colitis: an updated population-based systematic review and meta-analysis

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2025.7.31 ADHD

a) Evaluating ADHD medication trial representativeness: a Swedish population-based study comparing hypothetically trial-eligible and trial-ineligible individuals          
b) The Prevalence of Attention Deficit Hyperactivity Disorder in Psychotic Disorders: Systematic Review and Meta-analysis          
c) Emotion processing difficulties in ADHD: a Bayesian meta-analysis study

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2025.7.31 IBD

a) Appendicectomy plus standard medical therapy versus standard medical therapy alone for maintenance of remission in ulcerative colitis (ACCURE): a pragmatic, open-label, international, randomised trial        
b) Isolated perianal Crohn’s Disease: a systematic review and expert consensus proposing novel diagnostic criteria and management advice        
c) Defining radiological healing in perianal fistulising Crohn’s Disease: a TOpClass global expert Delphi consensus

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2025.7.29 IBD

a) Capsule endoscopy-guided proactive treat-to-target versus continued standard care in patients with quiescent Crohn's disease: A randomized controlled trial         
b) Definitions, diagnosis, and management of postoperative recurrence in Crohn’s Disease patients with permanent ileostomy-A systematic review and meta-Analysis         

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2025.6.30 ADHD

a) Review: Animal-assisted intervention for children with attention-deficit/hyperactivity disorder – a systematic review and meta-analysis       
b) Physical and neurophysiological maturation associated with ADHD among previously institutionalized children: a randomized controlled trial       
c) Comparative effectiveness of physical activity interventions on cognitive functions in children and adolescents with Neurodevelopmental Disorders: a systematic review and network meta-analysis of randomized controlled trials

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2025.6.30 IBD

a) Spleen volume in relation to Ulcerative Colitis and Crohn’s Disease: a Mendelian randomization study     
b) Surveillance in inflammatory bowel disease: white light endoscopy with segmental re-inspection versus dye-based chromoendoscopy – a multi-arm randomised controlled trial (HELIOS)     
c) Definitions, Diagnosis and Management of Postoperative Recurrence in Crohn’s Disease Patients with Permanent Ileostomy - A Systematic Review and Meta-Analysis

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2025.6.30 IBD

a) Evaluating the Efficacy of Probiotics on Disease Progression, Quality of Life, and Nutritional Status Among Patients with Crohn’s Disease: A Multicenter, Randomized, Single-Blinded Controlled Trial     
b) Novel Microbial Engraftment Trajectories Following Microbiota Transplant Therapy in Ulcerative Colitis   
c) Reliability and Responsiveness of Clinical and Endoscopic Outcome Measures in Crohn’s Disease

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2025.5.30 ADHD

a) The efficacy of behavioral sleep intervention on sleep problems among children with attention deficit hyperactivity disorder: A randomized controlled trial      
b) Impact of a physical exercise intervention on psychological resilience and mental ill-being in medical-naïve children with attention deficit hyperactivity disorder: a pilot randomized controlled trial     
c) Neurofeedback for Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis

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2025.5.30 IBD

a) Modified Crohn’s Disease Exclusion Diet Maintains Remission in Pediatric Crohn’s Disease: Randomized Controlled Trial      
b) Risk factors for inflammatory bowel disease: an umbrella review      
c) Assessment of activity and severity of inflammatory bowel disease in cross-sectional imaging techniques: a systematic review

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2025.5.29 IBD

a) Assessment and Reporting of Extraintestinal Manifestations and Fatigue in Phase 3 Inflammatory Bowel Disease Clinical Trials      
b) Operating Properties of Disease Activity Indices in Pediatric Inflammatory Bowel Disease: A Systematic Review      
c) A meta-analysis of the gut microbiome in inflammatory bowel disease patients identifies disease-associated small molecules

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2025.4.28 ADHD

a) Innovations in Practice: Brief behavioral parent training for children with impairing ADHD characteristics – a pilot study     
b) Impulsivity in ADHD and Borderline Personality Disorder: A Systematic Review of Gray and White Matter Variations     
c) A Systematic Review on Social Cognition in ADHD: The Role of Language, Theory of Mind, and Executive Function

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2025.4.28 IBD

a) Mechanistic implications of the Mediterranean diet in patients with newly diagnosed Crohn's disease- multi-omic results from a prospective cohort     
b) Systematic Review on definitions of Intestinal Ultrasound Treatment Response and Remission in Inflammatory Bowel Disease     
c) Dietary Interventions and Supplementation in Patients With an Ileal Pouch–Anal Anastomosis: A Systematic Review

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2025.4.25 IBD

a) Artificial intelligence–enabled histology exhibits comparable accuracy to pathologists in assessing histological remission in ulcerative colitis: a systematic review, meta-analysis, and meta-regression     
b) Meta-Analysis: Exclusive Enteral Nutrition in Adults With Ulcerative Colitis     
c) Network Meta-Analysis: Comparison of Endoscopic Dysplasia Detection Technologies in Inflammatory Bowel Disease

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2025.3.31 ADHD

a) Systematic Review: Assessment of Blinding Integrity in 161 Randomized Controlled Trials of Medications for Attention deficit / hyperactivity disorder      
b) A systematic review and meta-analysis comparing the severity of core symptoms of attention deficit hyperactivity disorder in females and males      
c) Exploring the impact of probiotics on adult ADHD management through a double-blind RCT

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2025.3.31 IBD

a) Acute Severe Ulcerative colitis: An International Delphi Consensus on Clinical Trial Design and Endpoints       
b) Modifiable psychological factors are associated with clusters of pain, fatigue, faecal incontinence and IBS-type symptoms in inflammatory bowel disease: a latent profile analysis       
c) Rigorous Donor Selection for Fecal Microbiota Transplantation in Active Ulcerative Colitis: Key Lessons From a Randomized Controlled Trial Halted for Futility

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2025.3.31 IBD

a) Nutritional Management in Stricturing Crohn’s disease: A Pilot Study       
b) Efficacy and Safety of Anthocyanin-Rich Extract in Patients with Ulcerative colitis: A Randomized Controlled Trial       
c) Multi-Omics Biomarkers for Predicting Efficacy of Biologic and Small-Molecule Therapies in Adults With Inflammatory bowel disease: A Systematic Review

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2025.2.28 IBD

a) Partial Enteral Nutrition in the Management of Crohn’s Disease: A Systematic Review and Meta-Analysis     
b) Preliminary results from a multicenter, randomized trial using fecal microbial transplantation to induce remission in patients with mild to moderate Crohn’s Disease      
c) Telemonitoring of Active Inflammatory bowel disease Using the App TECCU: Short-Term Results of a Multicenter Trial of GETECCU 

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2025.2.27 IBD

a) Repeated endoscopic dilation and needle-knife stricturotomy for Crohn's disease strictures     
b) A Core Outcome Set for Inflammatory Bowel Diseases: Development and Recommendations for Implementation in Clinical PracticeThrough an International Multistakeholder Consensus Process      
c) Vascular endothelial growth factor in inflammatory bowel disease: A systematic review and meta-analysis 

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2025.1.31 IBD

a) Eosinophils and risk of ulcerative colitis in European population: Evidence from Mendelian randomization study      
b) Therapeutic and Immunologic Effects of Short-Chain Fatty Acids in Inflammatory Bowel Disease: A Systematic Review      
c) Mendelian randomization reveals predictive, preventive, and personalized insights into inflammatory bowel disease: the role of gut microbiome and circulating inflammatory proteins

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2025.1.31 IBD

a) The association between bilirubin concentrations and inflammatory bowel disease: Insights from a systematic review and meta-analysis       
b) Meta-analysis: Risk of lymphoma in patients with inflammatory bowel disease in population-based cohort studies       
c) Gut Microbiota Features in Relation to Fecal Microbiota Transplantation Outcome in Ulcerative Colitis: A Systematic Review and Meta-Analysis

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2024.12.24 IBD

a) Harms with placebo in trials of biological therapies and small molecules as induction therapy in inflammatory bowel disease: a systematic review and meta-analysis     
b) Harms with placebo in trials of biological therapies and small molecules as maintenance therapy in inflammatory bowel disease: a systematic review and meta-analysis     
c) Rates of Endoscopic Recurrence In Postoperative Crohn's Disease Based on Anastomotic Techniques: A Systematic Review And Meta-Analysis

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2024.12.09 IBD

a) Comparing the Diagnostic Value of FDG PET or PET/CT with FDG PET/MR in Inflammatory Bowel Disease-A Systematic Review and Meta-analysis     
b) The impact of group cognitive behavioral psychotherapy on disease severity and psychosocial functioning in patients with inflammatory bowel disease: a randomized controlled study     
c) Oxidative stress-related biomarkers as promising indicators of inflammatory bowel disease activity: A systematic review and meta-analysis

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2024.11.27 IBD

a) Chronic Kidney Disease in Inflammatory bowel disease: a Systematic Review and Meta-analysis 
b) Prevalence of Sexual Dysfunction In Inflammatory bowel disease: Systematic Review and Meta-Analysis 
c) Emerging role of environmental pollutants in Inflammatory bowel disease risk, outcomes and underlying mechanisms

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2024.11.12 IBD

a) A global consensus on the definitions, diagnosis and management of fibrostenosing small bowel Crohn’s disease in clinical practice      
b) Whole blood DNA methylation changes are associated with anti-TNF drug concentration in patients with Crohn's disease      
c) Efficacy and safety of probiotics in IBD: An overview of systematic reviews and updated meta-analysis of randomized controlled trials 

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2024.10.21 IBD

a) Effect of mesenteric sparing or extended resection in primary ileocolic resection for Crohn's disease on postoperative endoscopic recurrence (SPICY): an international, randomised controlled trial     
b) Systematic review: Patient-related, microbial, surgical, and histopathological risk factors for endoscopic post-operative recurrence in patients with Crohn's disease     
c) Effect of hydrogel drug delivery system for treating ulcerative colitis: A preclinical meta-analysis 

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2024.10.04 IBD

a) Fungal Microbiota Composition in Inflammatory Bowel Disease Patients: Characterization in Different Phenotypes and Correlation With Clinical Activity and Disease Course    
b) Single-Cell Transcriptomic and Targeted Genomic Profiling Adjusted for Inflammation and Therapy Bias Reveal CRTAM and PLCB1 as Novel Hub Genes for Anti-Tumor Necrosis Factor Alpha Therapy Response in Crohn’s Disease    
c) Early Biologic Treatment Decreases Risk of Surgery in Crohn’s Disease but not in Ulcerative Colitis: Systematic Review and Meta-Analysis

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